Intravenous (IV) therapy is a critical medical procedure used to deliver fluids, medications, and nutrients directly into the bloodstream, but it carries risks such as infection, infiltration, phlebitis, and air embolism. Ensuring patient safety begins with a thorough assessment of medical history, allergies, current health status, and vein suitability, avoiding scarred, thrombosed, or infected veins. Sterile techniques, proper vein selection, and careful catheter insertion are crucial to minimize complications, with forearm and hand veins commonly used. Regular site inspection and monitoring for signs of complications, such as swelling, redness, or tenderness, allow for prompt intervention. Adherence to physician orders, accurate infusion rates, and patient education further enhance the therapy\'s safety and effectiveness.