Challenges and Innovations in Organ Transplant Immunosuppressant Drugs Therapy

The study of how genes affect a person's response to drugs is paving the way for personalized immunosuppressant therapy. Pharmacogenomic testing can help identify genetic variations that influence drug metabolism and response, allowing for tailored dosing and improved outcomes. For example, genetic testing for CYP3A5 polymorphisms can guide dosing of tacrolimus, a commonly used immunosuppressant.