Effectiveness of Mesotherapy for Cellulite Reduction Introduction Cellulite is a common cosmetic concern that affects both women and men, though it is far more visible in women due to differences in fat distribution, skin structure, and hormones. It appears as a dimpled or “orange peel” texture on areas such as the thighs, buttocks, hips, and abdomen. While cellulite is not a medical condition, many people seek treatments to improve skin smoothness and firmness. Mesotherapy has become one of the non-surgical options used for cellulite reduction. It involves injecting active substances into the middle layer of the skin to improve circulation, break down fat deposits, and enhance skin texture. But how effective is it really? This article explores how mesotherapy works for cellulite and what results can realistically be expected.